The most recent study on patients and treatment plans is the Guatemalan Guide for Antiretroviral and Opportunistic Infections Treatment, released in 2013. According to this guide, 92% of people who live with HIV and get their treatment by the Ministry of Public Health and Social Assistance (MSPAS), are on first line, 7% of patients are on second line, and the remaining 1% is on third line.
Guatemala is one of the countries with the most cocktail medications available, in the 2015-18 period there are up to 65 different combinations.